Preheat your oven to 375°F (190°C) and cut 1 large spaghetti squash in half lengthwise.
Scoop out the seeds, then roast the squash halves face-down on a baking sheet for 35-40 minutes.
Once cooked, use a fork to scrape out the spaghetti-like strands into a large mixing bowl.
Brown 1 pound of ground beef or sausage in a skillet, seasoning with Italian herbs and garlic.
Mix the cooked meat with the spaghetti squash, 1 cup marinara sauce, and 1 cup shredded mozzarella.
Transfer the mixture to a greased casserole dish, spreading it out evenly.
Top with additional mozzarella cheese, pepperoni slices, and your favorite pizza toppings.
Bake the casserole for 20-25 minutes until the cheese is bubbly and golden.
Serve the Spaghetti Squash Pizza Casserole hot, garnished with fresh basil or parsley.
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